Rub the Miswak on the teeth horizontally.
Whenever you intend to use the Miswak, use it at least three times.
Wash it each time.
Hold the Miswak in the right hand in such a manner that the little finger remains at the bottom, and the middle three fingers remain on it while the thumb remains at the top bristle end of Miswak.
First clean the top right row of the teeth and then the top left row. Then clean the bottom right row and then the bottom left row of the teeth.
To perform Miswak while holding it in a fist may cause piles.
Miswak is a pre-Wudu Sunnah. However, it becomes Sunnat-ul-Muakkadah when foul smell comes from the mouth. (Derived from: Fatawa Razawiyyah, vol. 1, pp. 623)
If the Miswak is no longer useable, do not throw it away as it is a means of acting upon a Sunnah. Rather, keep it somewhere respectfully or bury it or, after tying something heavy like a stone etc., put it into the sea-water.
(In order to get detailed information, study the book Bahar-e-Shari’at, volume 1, pages 294-295, published by Maktaba-tul-Madinah.)